Hi-Blood 120’s

Our Hi-Blood supplement is intricately formulated to engage with the body’s physiological processes related to high blood pressure. The combination of vital vitamins and specialized plant extracts contributes to the modulation of arterial plaque, mitigates inflammation in arterial walls, and regulates blood pressure dynamics. These actions aim to optimize the body’s inherent mechanisms in managing high blood pressure.

High Blood Pressure (Hypertension) Overview:

High blood pressure, or hypertension, is a prevalent cardiovascular condition that denotes elevated blood pressure within the arteries. This condition results from the force exerted by blood against the artery walls consistently being too high. Blood pressure readings are typically expressed as two numbers: systolic pressure over diastolic pressure. The systolic pressure represents the force when the heart contracts, while diastolic pressure is the force when the heart is at rest between beats. Normal blood pressure is approximately 120/80 mm Hg.

Hypertension poses a significant health risk as it places strain on the heart, damages blood vessels, and escalates the likelihood of severe health complications, including heart disease, stroke, and kidney disease. Various factors contribute to the development of hypertension, encompassing genetics, age, dietary choices, lifestyle factors, and underlying health conditions.

Causes of High Blood Pressure:
The exact causes of hypertension can be multifaceted. Genetic predisposition plays a role, and as individuals age, the risk of developing high blood pressure increases.

Unhealthy lifestyle choices, such as a diet high in sodium, lack of physical activity, excessive alcohol consumption, and tobacco use, contribute significantly to its onset. Additionally, underlying health conditions like kidney disease, hormonal disorders, and sleep apnea can elevate blood pressure.

Effects on the Body:

The consequences of untreated high blood pressure are profound. The increased pressure strains the heart, leading to hypertrophy or enlargement of the heart muscle, which can impair its function over time.

Persistent hypertension damages the delicate inner lining of arteries, promoting the formation of plaques, and contributing to atherosclerosis. This arterial damage raises the risk of blood clots, heart attacks, and strokes. Moreover, hypertension is a leading cause of kidney disease, as the high pressure can impair the kidneys’ ability to filter blood effectively.

Normal Blood Pressure and Danger Levels:

Normal blood pressure is typically measured as two values – systolic pressure over diastolic pressure. The normal range is around 120/80 mm Hg, where 120 represents the systolic pressure (pressure during heartbeats), and 80 represents the diastolic pressure (pressure between heartbeats).

However, blood pressure is a dynamic parameter, and what is considered normal can vary based on individual factors, including age, sex, and overall health. In general, though, readings consistently above 130/80 mm Hg may be indicative of elevated blood pressure, and healthcare professionals may monitor such individuals closely.

Dangerous or high-risk blood pressure levels are categorized into different stages:

1. Elevated Blood Pressure (Stage 1 Hypertension): Systolic pressure between 130-139 mm Hg or diastolic pressure between 80-89 mm Hg.
2. High Blood Pressure (Stage 2 Hypertension): Systolic pressure of 140 mm Hg or higher or diastolic pressure of 90 mm Hg or higher.
3. Hypertensive Crisis: This is a medical emergency. Systolic pressure is higher than 180 mm Hg, and/or diastolic pressure is higher than 120 mm Hg. Immediate medical attention is required.

Ingredients which are traditionally used for this disorder
Technical info:

Alfalfa Herb: Alfalfa is rich in vitamin K, which is essential for activating clotting factors in the liver, supporting blood coagulation. It also contains saponins that bind cholesterol and reduce LDL levels, while isoflavones like formononetin enhance nitric oxide production by stimulating endothelial estrogen receptors. These actions improve arterial elasticity and lower cardiovascular risk in individuals with fragile or plaque-prone arteries.

Ashwagandha: Ashwagandha helps clear arterial plaque by reducing systemic inflammation and cortisol-induced vasoconstriction. Withanolides modulate the hypothalamic-pituitary-adrenal (HPA) axis and promote nitric oxide release through endothelial activation, relaxing smooth muscle in arteries. It lowers blood pressure by decreasing sympathetic tone and improving vascular responsiveness under stress.

Bearberry Leaves (Uva Ursi): Bearberry lowers blood pressure by acting as a mild diuretic. Arbutin is metabolized to hydroquinone in the urine, stimulating renal elimination of sodium and water. This reduces plasma volume and preload, decreasing pressure in the renal and systemic circulations. Its antiseptic action also helps maintain healthy kidney function for long-term blood pressure control.

Bedstraw (Cleavers): Cleavers lowers blood pressure by enhancing lymphatic drainage and promoting renal clearance of excess fluids. Iridoid glycosides and phenolic acids stimulate interstitial fluid transport and reduce systemic volume load. This relieves pressure in the venous return system and indirectly improves arterial pressure in cases of fluid retention.

Bilberry Berries: Bilberry helps clear vascular plaque and supports microcirculation. Anthocyanins like delphinidin and cyanidin enhance endothelial nitric oxide synthase (eNOS), increasing vasodilation in small arteries and retinal vessels. These compounds also protect against oxidative damage and improve blood flow in fragile or constricted capillaries.

Bladderwrack: Bladderwrack supports arterial cleaning and restores vessel wall elasticity. Fucoidan reduces vascular inflammation and improves endothelial healing, while iodine stimulates thyroid hormone synthesis, increasing metabolic rate and enhancing peripheral circulation. These actions tone arterial walls and remove fatty deposits that cause stiffness.

Bromelain: Bromelain clears plaque and improves blood flow by breaking down fibrin and reducing blood viscosity. It inhibits inflammatory mediators like bradykinin and prostaglandins, relaxing vascular tone and improving capillary perfusion. Its proteolytic action supports arterial flexibility and reduces clot formation risk in hypertensive conditions.

Buckwheat Herb: Buckwheat strengthens arteries and prevents vascular hardening. Rutin and quercetin improve endothelial function by inhibiting angiotensin-converting enzyme (ACE) and reducing oxidative stress. These flavonoids preserve nitric oxide levels, enhance vasodilation, and support capillary strength, especially in hypertensive and diabetic individuals.

Cat’s Claw: Cat’s claw lowers blood pressure, acts as a diuretic, relaxes smooth muscle, and dilates vessels. Pentacyclic oxindole alkaloids (POAs) suppress inflammatory mediators like TNF-α in the endothelium, while quinovic acid glycosides promote nitric oxide release. This dual mechanism enhances circulation and reduces vascular resistance.

Cayenne Pepper: Cayenne regulates blood pressure and acts as a solvent to liquefy impurities in arteries. Capsaicin activates TRPV1 receptors on vascular and sensory neurons, triggering nitric oxide and prostacyclin release. This vasodilates arteries and reduces sympathetic tone, while also improving metabolic circulation and endothelial health.

Coriander Seed (Cilantro): Coriander lowers blood pressure through apigenin and linalool, which activate nitric oxide release and relax smooth muscle in peripheral arteries. These compounds support cholinergic function and modulate calcium flow, easing vascular tension. Its diuretic action enhances renal sodium excretion, reducing circulating volume and aiding in pressure normalization.

Dandelion Herb: Dandelion regulates blood pressure by acting as a natural diuretic. Taraxasterol and chlorogenic acid inhibit renal Na⁺/K⁺-ATPase, promoting sodium and water excretion while protecting glomerular function. Dandelion also supports hepatic detoxification, reducing systemic inflammatory load and preserving endothelial function—particularly beneficial in fluid-related hypertension.

Dong Quai Root (Angelica): Dong Quai lowers blood pressure and supports arterial tone through ferulic acid and ligustilide. These compounds reduce vascular resistance by inhibiting endothelin-1 and enhancing nitric oxide synthesis. Dong Quai improves coronary and cerebral blood flow and has adaptogenic effects on autonomic tone, helping prevent hypertension caused by hormonal or stress-related dysregulation.

Garlic: Garlic regulates blood pressure and helps dissolve arterial plaque. Allicin, formed when raw garlic is crushed, inhibits ACE, reduces lipid levels, and improves nitric oxide bioavailability. It lowers cholesterol and suppresses oxidative stress in vascular walls. By thinning the blood and reducing clot formation, garlic protects against atherosclerosis and promotes arterial elasticity.

Ginger: Ginger improves circulation, clears plaque, and reduces clot risk. Gingerol and shogaol inhibit calcium channels in smooth muscle, promoting vasodilation. These compounds activate TRPV1 and reduce NF-κB–mediated inflammation, enhancing peripheral blood flow and preventing thrombus formation. Ginger supports endothelial health, particularly in individuals with metabolic or inflammatory hypertension.

Ginkgo Biloba (Maidenhair Tree): Ginkgo regulates blood pressure and improves circulation through terpenoids and flavonoids like bilobalide and ginkgolide B. These inhibit platelet-activating factor (PAF) and enhance nitric oxide release in microvessels. Ginkgo reduces vascular tone and blood viscosity, improving cerebral perfusion and reducing pressure in small arteries, especially in the brain and retina.

Ginseng Root (Siberian): While ginseng is an adaptogen with tonic effects, Siberian ginseng may raise blood pressure in some individuals. Eleutherosides B and E modulate stress response and adrenal output. In certain hypertensive people, it can increase sympathetic tone and vascular resistance. It is best used cautiously or avoided if elevated blood pressure is present unless proven to lower BP in a specific individual.

Guggul Lipid: Guggul clears plaque and supports lipid balance. Guggulsterones antagonize farnesoid X receptors (FXR), reducing hepatic cholesterol synthesis and promoting bile excretion. This action lowers blood lipids and reduces vascular load. Guggul also inhibits NF-κB in vascular tissues, reducing inflammation and preserving endothelial flexibility.

Hawthorn Berries/Leaves: Hawthorn regulates blood pressure, reduces plaque blockages, and tones the heart. Oligomeric procyanidins and flavonoids like vitexin and hyperoside dilate coronary arteries, enhance myocardial perfusion, and reduce endothelial inflammation. These compounds also improve nitric oxide production and decrease angiotensin II activity, easing vascular tension. Hawthorn strengthens heart muscle and stabilizes rhythm, especially under emotional or stress-induced cardiac strain.

Magnesium Bisglycinate: Magnesium is a natural calcium channel blocker, promoting smooth muscle relaxation and lowering systemic resistance. It stabilizes nerve conduction in autonomic ganglia and cardiac tissue, reducing sympathetic output. Magnesium regulates sodium and potassium handling in renal tubules and supports ATP-dependent vascular function. Deficiency contributes to hypertension, arrhythmias, and arterial stiffness.

Mistletoe: Mistletoe lowers blood pressure by acting directly on the autonomic centers of the brain and peripheral vascular system. Viscotoxins and lectins inhibit angiotensin II synthesis and enhance nitric oxide activity, reducing vasoconstriction and improving endothelial flexibility. Mistletoe also modulates parasympathetic tone, stabilizing heart rate and supporting balanced circulatory output, particularly helpful in nervous or autonomic hypertension.

MSM (Methylsulfonylmethane): MSM clears plaque and reduces vascular inflammation. It supplies bioavailable sulfur for glutathione synthesis and methylation reactions. MSM inhibits NF-κB and prostaglandin E2 production, protecting endothelial cells from chronic inflammation. It improves microcirculation and reduces oxidative stress, supporting arterial resilience and fluid regulation.

Sage: Sage lowers blood pressure by reducing oxidative stress in the vascular system. Rosmarinic acid and carnosic acid inhibit ACE, support endothelial nitric oxide release, and reduce endothelin-1 expression. Sage also acts centrally to reduce autonomic overstimulation and promotes parasympathetic dominance. This leads to improved arterial flexibility and lower resistance, especially in cerebral and digestive circulation.

Sassafras Wood: Sassafras acts as a solvent for vascular impurities and supports circulation. Safrole and eugenol derivatives relax vascular smooth muscle and modulate GABAergic tone in the central nervous system. This calms sympathetic activity and improves perfusion in tissues with poor arterial flow. Sassafras also mildly enhances hepatic detoxification, indirectly benefiting vascular pressure.

Turmeric: Turmeric clears plaque and reduces blood pressure via curcumin, which inhibits NF-κB and promotes nitric oxide synthesis. Curcumin reduces proteinuria, protects kidneys from oxidative stress, and improves endothelial function. Turmeric’s absorption is poor alone but is greatly enhanced by black pepper (piperine) and fat. When properly absorbed, it improves vascular tone, reduces inflammation, and protects arterial linings.

Valerian Root: Valerian regulates blood pressure through central sedation. Valerenic acid enhances GABA activity in the brainstem, reducing sympathetic output and promoting parasympathetic dominance. This calms heart rate and reduces vascular tension. It is especially helpful for stress-induced or neurogenic hypertension accompanied by anxiety or sleep disturbances.

Veronica Speedwell: Veronica lowers blood pressure and helps remove arterial plaque. Iridoid glycosides like aucubin reduce endothelial inflammation and enhance nitric oxide production. It also improves lymphatic drainage and capillary strength, reducing arteriosclerosis and systemic vascular resistance, particularly in fragile or inflamed vasculature.

Vitamin B12 – Cyanocobalamin: Vitamin B12 helps clear arterial plaque by reducing homocysteine levels, a known risk factor for endothelial dysfunction. It serves as a cofactor for methionine synthase, converting homocysteine into methionine in hepatocytes and vascular tissues. This protects against arterial inflammation and stiffness, particularly in cerebral and renal arteries, and supports blood formation, reducing compensatory vasoconstriction.

Vitamin B6 – Pyridoxine: B6 clears plaque and lowers blood pressure by regulating homocysteine metabolism through cystathionine β-synthase. It is essential for neurotransmitter synthesis and modulates sympathetic output by balancing norepinephrine and dopamine levels. B6 helps reduce oxidative injury to the endothelium and supports nitric oxide production, enhancing arterial flexibility.

Vitamin C – Ascorbic Acid Powder: Vitamin C helps repair inner vessel walls and reduces arteriosclerosis. It stimulates eNOS activity and regenerates tetrahydrobiopterin (BH4), a vital cofactor for nitric oxide synthesis. It also scavenges free radicals that degrade NO, preserving endothelial function. Vitamin C supports collagen synthesis in vascular connective tissue and lowers inflammation in arterial linings.

Vitamin D3 – Cholecalciferol: Vitamin D3 clears plaque and supports blood pressure by downregulating renin expression in juxtaglomerular kidney cells. This reduces angiotensin II–mediated vasoconstriction and sodium retention. Vitamin D also enhances calcium regulation in vascular smooth muscle and improves endothelial integrity, especially in patients with metabolic or inflammatory hypertension.

Vitamin E – Alpha Tocopherol Acetate: Vitamin E reduces inflammation in arterial walls and strengthens them. As a lipid-soluble antioxidant, it protects polyunsaturated fatty acids in cell membranes from oxidation. It preserves nitric oxide signaling and inhibits adhesion molecule expression in the endothelium, reducing vascular stiffness and atherogenic activity.

Wild Garlic (Ramsons): Wild garlic lowers blood pressure more effectively than cultivated garlic due to higher levels of allicin, ajoenes, adenosine, magnesium, and phosphorus. These compounds reduce LDL, improve nitric oxide synthesis, and inhibit platelet aggregation. Wild garlic protects endothelial function and reduces cholesterol more efficiently, making it valuable for both pressure control and atherosclerotic reversal.

Zinc Glycinate: Zinc supports vascular stability and nitric oxide production. It is a cofactor for antioxidant enzymes like Cu/Zn superoxide dismutase, protecting endothelial cells from oxidative stress. Zinc also regulates calcium channels and stabilizes eNOS, enhancing vasodilation. Deficiency is associated with increased blood pressure due to endothelial dysfunction and inflammation.